Sr. Computational Chemist

Location: South San Francisco, California Salary: competitive
Sector: Pharma & Biotech, Engineering & Validation, R&D, Datenmanagement und Biostatistik, R&D Type: Permanent

Our client is looking for a highly experienced Sr. Computational Chemist to join their discovery team. The ideal candidate will be able to work both independently and cross-functionally while maintaining the great culture currently established. This position has the opportunity to develop into a leadership role withing the company.


  • PhD in Computational Chemistry or related
  • 5+ Years Pharmaceutical Experience
  • Working knowledge of computer-aided drug design, scientific programming, and molecular modeling (Knime, Gold, MOE, Maestro, Schrodinger, ect.)
  • Working knowledge of computational software packages


  • Experience developing models from mining databases
  • Broad experience using computational chemistry techniques


  • Establish the companies modeling capabilities through software development
  • Partner and collaborate with discovery teams in the designing, optimization, and acceleration of novel drug candidates
  • Use modeling and data-mining to enhance strategy and the understanding of SAR
  • Apply molecular dynamics to understand SAR and drug binding
  • Develop new approaches to design bioactive-relevant features
  • Lead the computational chemistry efforts on multiple projects

Sthree US is acting as an Employment Agency in relation to this vacancy.